Regulation of transcription by cyclin-dependent kinases (CDKs) in human cells

Biography:

Michael Tellier originally studied microbiology at the University Paris VII and Institute Pasteur (group of Prof. Didier Mazel) in Paris, France. He then moved to the University of Nottingham, UK, for his doctoral work in the group of Prof. Ronald Chalmers. He investigated during his PhD the functions in gene expression and DNA repair of SETMAR, a primate-specific protein resulting from the fusion of a histone methyltransferase and a domesticated DNA transposase. Subsequently, Michael moved as a postdoctoral researcher to the group of Prof. Shona Murphy at the University of Oxford, UK, where he is investigating in human cells the functions of a group of kinases, called cyclin-dependent kinases (CDKs), in transcription and co-transcriptional processes. His current work addresses how protein phosphorylation is involved in the coordination between transcription and some of the co-transcriptional processes, such as mRNA splicing, mRNA cleavage and polyadenylation, and mRNA export.