Principal Investigators GRE

Principal Investigators

Principal Investigator in Genome Dynamics Job Reference: SLSC0583

Closing Date: 1st July 2019

The Centre for Gene Regulation and Expression, within the School of Life Sciences at the University of Dundee, consists of 14 research groups studying different aspects of genome function. Within these labs over one hundred postdoctoral and postgraduate scientists work in a collaborative environment to address different aspects of genome biology and structure. A special strength of the centre is our co-operative effort to establish and maintain state of the art technologies used for studying gene regulation. These include advanced light microscopy, proteomics, genomics, X-ray crystallography, cryo-electron microscopy, cell sorting and data analysis capabilities. The School of Life Sciences was ranked as the number 1 University Biological department in REF2014 and consistently ranks within the top 10 Institutes world-wide for citations per paper (QS World University Rankings). There are over 80 different research groups within the School of Life Sciences and this provides access to expertise and facilities across a full range of subjects within molecular and cellular life sciences.

Applications are sought from researchers seeking to establish an independent research group in all areas of genetic regulation. This includes groups studying how genomes are maintained and inherited following cell division and the regulation of gene expression at different levels from chromatin through RNA metabolism to protein stability. We study these processes in normal cells and in disease models being well placed to develop inhibitors through interactions with our colleagues in the adjacent Drug Discovery Unit.

Successful applicants will be provided with a starting package that includes a defined transition to tenure after 5-6 years.  Typically this package would include financial support for relocation expenses, an allocated studentship and for purchase of essential start-up equipment. We expect applicants to obtain external fellowship support but are able to offer some start-up costs, if required. New researchers are supported by a structured mentoring programme that seeks to provide both project specific advice and guidance on establishing a strategy for long term funding. Combined with access to the research facilities available in Dundee, we believe this provides a very strong platform for the establishment of independent careers.

Applicants are expected to obtain external research funding and/or fellowship support. As a result we would normally expect applicants to have completed up to 6 years postdoctoral work following from their PhD. However, if a career break has been taken, this will be taken into consideration.

Applications  should  include  a  full  CV  and  list  of  publications,  the  names   and  contact  details of 3  academic referees, and a brief summary of future research plans.

For further information and informal enquiries please contact; Tom Owen-Hughes ( or Vicky Cowling (

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How to Apply

To enquire about a PI position, please submit an up to date CV, a cover letter explaining your interests and how these integrate with current GRE research. In addition, please include a short description of the proposed research you would like to undertake. Informal enquiries are also welcome and should be directed to Tom Owen-Hughes or Vicky Cowling. Formal applications to advertised positions should be made using the University of Dundee, online application system.

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